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rutin
All About Rutin:

An Introduction

"Buckwheat is not just another wheat."

What is Rutin ?

Rutin is a member of bioflavonoids, a large group of phenolic secondary metabolites of plants that include more than 2,000 different known chemicals. Bioflavonoids such as Quercetin, Rutin, and Hesperidin are important nutrients due to their ability to strengthen and modulate the permeability of the walls of the blood vessels including capillaries.

DreamPharm's lutein supplements Lutein-6 and Lutein-20 contain generous amounts of buckwheat (Fagopyrum esculentum), which is abundant (4-6% of the weight) with a flavonoid called Rutin, an active ingredient known to offer nutritional support to the circulatory systems including the capillaries in eyes with no side effects. Rutin has proved to be especially helpful in preventing recurrent bleeding caused by weakened blood vessels, so it has been used in the treatment of hemorrhoids and varicose veins, helping to prevent blood vessel walls becoming fragile. Rutin is safe and effective for: Poor Circulation, High Blood Pressure, Varicose Veins, Chilblains, Capillary Fragility, etc.

Buckwheat belongs to the family of Polygonaceae, and origniates from China, where buckwheat has been cultivated for at least 2,000 years. In addition to the common buckwheat Fagopyrum esculentum, a few variants have also been cultivated in Asia, Europe, and North America. Buckwheat has been cultivated and consumed in China, Korea and Japan for more than thousand years, in the form of buackwheat jello and buckwheat noodle (soba). Buckwheat has recently been found to be very effective in reducing high blood pressure and slowing the aging process. Buckwheat is easy to grow, and found almost everywhere along with other crops in Asian countries. Buckwheat was introduced to Europe around 15th century through Siberia.

Buckwheat is uniquely rich in proteins (12-15%) and essential amino acids such as lysine (5-7%) that are deficient in major cereal crops, and also abundant in lipid, minerals (iron, phosphorus, and copper), and vitamins (B1 and B2) and rutin. Rutin is found in buckwheat grains and plants (but not in other grains). Buckwheat has become a highly safe and healthy medicinal plant with efficacies for vascular disorders casued by abnormally fragile or permeable capillaries. Buckwheat flowers are important honey source in Korea and other Asian countries.


- Important micro-nutrients in buckwheat

1. Rutin (a bioflavonoid)

This special bioflavonoid is not found in other grains such as rice, wheat, etc. or beans, but is contained in great quantity (4-6%) in buckwheat. Rutin is important because it strengthens capillaries and so helps people suffering from arteriosclerosis (the hardening of the arteries) or high blood pressure. Rutin belongs to a group of plant compounds called bioflavonoids that also include the important catechins of green tea and the polyphenols of red wine. Recent studies have shown that the bioflavonoids are powerful antioxidants that fight free radicals. Free radicals are said to be responsible for as much as 90 percent of all the human diseases, such as cancer, arteriosclerosis, strokes, senility due to aging, etc.

2. Vitamin P

This vitamin is similar to rutin in that it increases capillary strength. But it is important in its own right because it is necessary for the proper functioning and absorption of vitamin C. Although buckwheat is the only significant source of vitamin P, this vitamin is also contained in trace amounts in rose hips, cherries, blackberries, prunes, skin and pulp of fruits, vegetables, etc.

3.Choline

This is a compound in the vitamin B complex that plays an important role in metabolism, lowers blood pressure, and hinders the deposition of fat in the liver. As a neutralizing agent, choline helps the function of the liver that has been particularly overburdened by alcoholic beverages. It makes sense that soba noodle soup is often served in Japan to the guests as a midnight snake after a heavy-drinking party.

- Major health benefits of buckwheat

1. Elimination of cholesterol

The high content of dietary fiber in buckwheat helps the body eliminate cholesterol, which in turn increases blood flow and therefore lowers blood pressure.

2. Prevention of fat accumulation

Although other grains contain protein, the buckwheat protein has been shown to be particularly powerful in preventing the accumulation of fat in the body.

3. Promotion of bowel movement

The dark skin of the buckwheat seeds ground into flour has an ability to stimulate the intestines, so the consumption of soba noodles promotes bowel movement.


Rutin Research:


Historically, buckwheat has been a food crop, and recently it is increasingly receiving attention as an important medicinal herb due to the discovery of health benefits of buckwheat and its main constituent, rutin.

Some examples of research reports on rutein and buckwheat are provided:

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=6380955&dopt=Abstract
Crit Rev Food Sci Nutr 1983;19(3):213-58 - Buckwheat: structure, composition, and utilization

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=8858269&dopt=Abstract
Eur J Clin Pharmacol 1996;50(6):443-7 - Leg oedema protection from a buckwheat herb tea in patients with chronic venous insufficiency: a single-centre, randomised, double-blind, placebo-controlled clinical trial

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10552821&dopt=Abstract
J Agric Food Chem 1999 Oct;47(10):4384-7 - Effect of processing on the flavonoid content in buckwheat (Fagopyrum esculentum Moench) grain

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11361045&dopt=Abstract
J Clin Pharmacol 2001 May;41(5):492-9 - Pharmacokinetics and bioavailability of quercetin glycosides in humans

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11920648&dopt=Abstract
Int J Cancer 2002 Apr 10;98(5):761-9 - Food-derived polyphenols inhibit pancreatic cancer growth through mitochondrial cytochrome C release and apoptosis

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11266652&dopt=Abstract
Biochem Pharmacol 2001 Mar 15;61(6):677-84 - Enhancement of antioxidant and anti-inflammatory activities of bioflavonoid rutin by complexation with transition metals

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11092407&dopt=Abstract
J Bone Miner Res 2000 Nov;15(11):2251-8 - Rutin inhibits ovariectomy-induced osteopenia in rats

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10917564&dopt=Abstract
Cell Biol Toxicol 2000;16(2):91-8 - Bioflavonoids as antiradicals, antioxidants and DNA cleavage protectors

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10904145&dopt=Abstract
J Ethnopharmacol 2000 Jul;71(1-2):45-53 - Evidence for protective and antioxidant properties of rutin, a natural flavone, against ethanol induced gastric lesions

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10812062&dopt=Abstract
FEBS Lett 2000 May 12;473(2):145-8 - Flavonoids can replace alpha-tocopherol as an antioxidant

reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10783313&dopt=Abstract
Carcinogenesis 2000 May;21(5):921-7 - Plant phenolics decrease intestinal tumors in an animal model of familial adenomatous polyposis

BMJ 2002;324:689-690 ( 23 March ) - New treatments for varicose veins




    The information provided at DreamPharm.com is for educational purposes only and is not intended for self-diagnosis nor self-treatment of conditions that should be managed by a qualified health care provider. Unless otherwise indicated, research, ailment and product information have not been evaluated by the US Food and Drug Administration ("FDA").

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