About Herbs and Nutrition
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About Black cohosh
About Angelica sinensis, Dong Quai
About menopause and PMS
Black cohosh research articles: abstracts and links to sources
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All About Black cohosh:
An Introduction
"Black Cohosh - A Lady's Herb."
What is Black Cohosh ?
Family: Ranunculaceae
Genus and Species: Cimicifuga racemosa
Black cohosh is native to eastern North America, where it is found growing in shady woods in the United States and Canada.
Black cohosh is a tall (9 feet high) herbaceous plant, and grows up on a stout, blackish rhizome (not radix, or true root), which
are hard, cylindrical, and knotty.
The white flowers of black cohosh produce unpleasant smell, and bloom on feathery racemes, which is long (up to 3 feet) and slender.
Native Americans used the rhizome of black cohosh to treat various ailments including kidney problems, sore throat, malaria, and rheumatism,
and women's problems such as menstrual irregularity. Black cohosh and blue cohosh (Caulophyllum thalictroides)
have been the favorite herbs
for gynecological complaints among native Americans, just like dong quai (or dang gui; Angelica sinensis,
a.k.a. lady's ginseng) and licorice have been favorite herbs for women in China and Korea.
History
Black cohosh and blue cohosh have been the favorite herbs for gynecological complaints among native Americans. Black cohosh was adapted and
used by early settlers and medical professionals, mostly for rheutamtoid ailments, and women's menstrual stress and nervous tension. As an
effective herb for reducing menopause-related symptoms, black
cohosh is one of the biggest sellers among herbs in the US today. Black cohosh and blue cohosh are two main
constituents of DreamPharms's product Menopause PMS formula.
Usage
German Commission E approved the use of black cohosh root for premenstrual discomfort and dysmenorrhea or menopausal neurovegetative ailments
and discomfort, including hot flashes and vaginal dryness.
Dose: 40 mg of cut rhizome of black cohosh per day is recommended. For standardized extract (1:1, standardized to 1% 27-deoxyacteine), 8 mg
per day is recommended.
Side effects: No side effect is known except occasional gastric discomfort. No interaction with other drugs is known.
Chemistry and Pharmacology
A rather complete chemical composition list of black cohosh can be found in Dr.
Duke's Phytochemical and Ethnobotanical Databases. Main constituents of black cohosh include oleic, palmitic, and salicylic acids;
cimigonite; tannin; and volatile oil. The tetracyclic triterpenes, which are oxidized and cyclicized by ketalization, are derived from cycloartanol
such as actein and cimifugoside. Commission E reported estrogen-like action, luteinizing hormone suppression, and binding to estrogen receptors.
[Herbal Medicine - Expanded Commission E monographs, by Mark Blumenthal, Alicia Goldberg, and Josef Brinckmann, first edition, 2000].
Black cohosh Research:
Black cohosh contains a potent and yet mild estrogen-like substances that affects endocrine regulations by weakly, and
transiently binding to estrogen receptors. The efficacy has been supported by numerous anecdotal avidences and testimonies.
Some examples of modern scientific and clinical research reports ond reviews on black cohosh are provided:
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11368622&dopt=Abstract
J Agric Food Chem 2001 May;49(5):2472-9 - Evaluation of estrogenic activity of plant extracts for the potential treatment of menopausal symptoms
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11875334&dopt=Abstract
Menopause 2002 Mar-Apr;9(2):145-50 - Estrogenic activity of herbs commonly used as remedies for menopausal symptoms
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11867271&dopt=Abstract
J Steroid Biochem Mol Biol 2002 Jan;80(1):125-30 - Antiestrogenic activities of Cimicifuga racemosa extracts
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11347288&dopt=Abstract
Altern Ther Health Med 2001 May-Jun;7(3):93-100 - Black cohosh: efficacy, safety, and use in clinical and preclinical applications
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11321955&dopt=Abstract
Wei Sheng Yan Jiu 2001 Mar;30(2):77-80 - Estrogenicity of black cohosh (Cimicifuga racemosa) and its effect on estrogen receptor level in
human breast cancer MCF-7 cells
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11352967&dopt=Abstract
J Clin Oncol 2001 May 15;19(10):2739-45 - Randomized trial of black cohosh for the treatment of hot flashes among women with a history
of breast cancer
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10730024&dopt=Abstract
J Am Pharm Assoc (Wash) 2000 Mar-Apr;40(2):234-42; quiz 327-9 - Herbs of special interest to women
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10531758&dopt=Abstract
J Am Med Womens Assoc 1999 Fall;54(4):181-3 - Hormone-modulating herbs: implications for women's health
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10523716&dopt=Abstract
Oncol Rep 1999 Nov-Dec;6(6):1383-7 - Growth inhibition of human breast cancer cells by herbs and phytoestrogens
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=10380441&dopt=Abstract
J Nurse Midwifery 1999 May-Jun;44(3):205-16 - A national survey of herbal preparation use by nurse-midwives for labor stimulation.
Review of the literature and recommendations for practice
reference source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9650153&dopt=Abstract
J Womens Health 1998 Jun;7(5):525-9 - A review of the effectiveness of Cimicifuga racemosa (black cohosh) for the symptoms of menopause
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