laxative



References: Laxative






Gut. 1988 Jul;29(7):969-73.
Outcome of colectomy for severe idiopathic constipation.

Kamm MA, Hawley PR, Lennard-Jones JE.

St Marks Hospital, London.

Severe idiopathic constipation affects predominantly young women. We have evaluated the results of colectomy in 44 women with a normal diameter colon and with a median bowel frequency of once per four weeks. The operations were done in one hospital over a 15 year period. After operation 22 patients had normal bowel frequency, 17 diarrhoea (greater than three bowel actions/day), and five persistent or recurrent constipation (interval between bowel actions at least three days). Many patients continued to experience abdominal pain (98% preoperatively v 71% postoperatively); straining and laxative use were still common after surgery. Ten patients needed psychiatric treatment for severe psychological disorders. The preoperative abnormalities of paradoxical contraction of the pelvic floor during straining and impaired rectal evacuation of a water filled balloon did not correlate with the outcome.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=3396968&dopt=Abstract constipation laxative



Zhonghua Wai Ke Za Zhi. 1996 Jul;34(7):438-9.
[Treatment of recurrent anterior dislocation of the shoulder with pectoralis minor muscle-bone flap]

[Article in Chinese]

Lin A, Jin M, Chen J.

Department of Orthopaedics of Nanfang Hospital, First Military Medical University, Guangzhou.

We treated 10 patients with recurrent anterior dislocation of the shoulder by transplantation of pectoralis minor muscle-bone flap transplanted to the upper part of the humerus. All patients were followed-up for an average 31 months and no recurrent was found. We consider that the muscle beily exerts a protective effect like a barrier on the weak anterio inferior region of the shoulder and increases the force for extending the shoulder and lifting the arm. The operation is based on biomechanics. Meanwhile, suturing the laxative joint capsule and repairing the weak anteroinfeior region of the shoulder is more beneficial to prevent from redislocation of the humerus head.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9590801&dopt=Abstract constipation laxative



J Clin Gastroenterol. 1998 Apr;26(3):167-70.
Melanosis coli in inflammatory bowel disease.

Pardi DS, Tremaine WJ, Rothenberg HJ, Batts KP.

Inflammatory Bowel Disease Clinic and Division of Gastroenterology, Mayo Clinic and Foundation, Rochester, Minnesota, USA.

Melanosis coli is a relatively common condition in which pigment is deposited in macrophages in the colonic lamina propria. The association with anthraquinone laxatives is well described, but melanosis coli has also been described in patients not using these agents. We report 25 patients with inflammatory bowel disease and melanosis coli, 5 (20%) of whom had documented laxative use. Most patients had ulcerative colitis (72%) or Crohn's colitis (24%), and the mean duration of inflammatory bowel disease was more than 7 years. These data raise the possibility that chronic colitis could cause melanosis coli even in the absence of laxative use.

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=9600362&dopt=Abstract constipation laxative



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