References: Laxative
Eur Radiol. 2002 Jun;12(6):1410-5. Epub 2002 Apr 24.
Patient acceptance for CT colonography: what is the real issue?
Thomeer M, Bielen D, Vanbeckevoort D, Dymarkowski S, Gevers A, Rutgeerts P, Hiele M, Van Cutsem E, Marchal G.
Department of Radiology, University Hospitals, Herestraat 49, 3000 Leuven, Belgium.
The aim of this study was to evaluate the discomfort associated with CT colonography compared with colonoscopy and bowel purgation cleansing, and to evaluate patient preference between CT colonography and colonoscopy. In a total of 124 patients, scheduled for multidetector virtual CT colonography and diagnostic colonoscopy, patient acceptance and future preference were assessed during the different steps of the procedure (colon preparation, CT examination, and conventional colonoscopy). Patients who described contradictory findings between the degree of discomfort and their preference regarding follow-up examinations were retrospectively reinterviewed regarding the reason for this discrepancy. Colonoscopy was graded slightly more uncomfortable than virtual CT colonography, but the preparation was clearly the most uncomfortable part of the procedure. Concerning their preference regarding follow-up examinations, 71% of the patients preferred virtual CT colonography, 24% preferred colonoscopy, and 5% had no preference. Twenty-eight percent of the patients preferred virtual CT colonography despite that they thought it was equally or even more uncomfortable than colonoscopy. This was mainly due to the faster procedure (17 patients), the lower physical challenge (14 patients), and the lack of sedation (12 patients) of virtual CT colonography. Factors other than the discomfort related to the examinations play an important role in the patient's preference for virtual CT colonography, namely the faster procedure, the lower physical challenge, and the lack of sedation. Since the preparation plays a major decisive factor in the patient acceptance of virtual CT colonography, more attention should be given to f
Abdom Imaging. 2002 Jul-Aug;27(4):410-7.
Fecal tagging: MR colonography without colonic cleansing.
Lauenstein TC, Goehde SC, Debatin JF.
Department of Diagnostic Radiology, University Hospital Essen, Hufelandstrasse 55, D-45122 Essen, Germany.
Colorectal cancer, mostly arising (>90%) from preexisting adenomatous polyps, continues to be the second leading cause of cancer death. Magnetic resonance colonography (MRC) permits accurate detection of colonic polyps with a diameter larger than 10 mm. Because residual colonic stool cannot be differentiated from polyps, MRC requires a clean colon. However, the rigors associated with colonic cleansing considerably reduce patient acceptance. The need for colonic cleansing could be eliminated, if stool were to acquire a signal intensity different from polyps and identical to the enema used to fill and distend the colon. In principle, there are two approaches to this concept of fecal tagging: dark polyps surrounded by bright stool and a bright enema, and bright polyps surrounded by dark stool and a dark enema. The first approach has been evaluated with some success. Gadolinium (Gd)-DOTA was administered as an oral contrast agent with meals preceding MRC based on the administration of a Gd-based enema. The high cost of Gd-based contrast has limited the clinical utility of this technique. In the second approach patients are provided with barium as an oral fecal tagging agent to render stool dark, and barium for the enema is used to distend the colon during MRC. The colonic wall and polyps arising from it can be made visible after intravenous administration of Gd-based extracellular contrast. This method provides sufficient contrast between the darkened colonic lumen and the brightly enhanced colonic wall to permit virtual endoscopic rendering. Preliminary results showed an exact correlation with findings of conventional endoscopy and surgery. Fecal tagging obviates bowel cleansing and therefore should enhance patient acceptance for MR colonoscopy. Barium
Abdom Imaging. 2002 Jul-Aug;27(4):453-7.
Perforations of the rectosigmoid colon induced by cleansing enema: CT findings in 14 patients.
Gayer G, Zissin R, Apter S, Oscadchy A, Hertz M.
Department of Diagnostic Imaging, Sheba Medical Center affiliated to the Sackler School of Medicine, Tel Aviv University, Tel Hashomer 52621, Israel.
BACKGROUND: We report the computed tomographic (CT) features of colorectal perforations caused by cleansing enema. METHODS: We reviewed the medical records and CT studies of all patients with colorectal perforations caused by a cleansing enema. RESULTS: Fourteen patients (10 men, four women; average age = 80 years) were included in the study. The most common presenting symptoms were severe abdominal pain and fever. CT was performed within 48 h after the event in most patients. Extraluminal air in the perirectal fat was the most frequent finding on CT and was present in all patients. Additional findings were extraperitoneal ( n = 9), intraperitoneal ( n = 3) and /or subcutaneous ( n = 3) air, free fluid ( n = 9), extraluminal feces ( n = 8), and focal bowel wall thickening ( n = 4). No leak of contrast from the rectum was observed in any patient including the one patient in whom contrast was administered rectally. Ten patients were treated by surgery; five recovered and the other five died. The other four patients were treated conservatively and all four died. CONCLUSION: The diagnosis of colorectal perforation can be made on CT. Because the diagnosis is not always suspected by the clinician, the radiologist may be the first to suggest it. Therefore, the radiologist should be familiar with the CT features of a potentially lethal, rectally induced perforation.
Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=12066245&dopt=Abstract constipation laxative colon cleansing
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