References: Laxative
Scand J Gastroenterol. 1992;27(1):25-8.
Breath methane and colorectal cancer.
Sivertsen SM, Bjorneklett A, Gullestad HP, Nygaard K.
Surgical Dept., Ulleval Hospital, Oslo, Norway.
The association between colorectal cancer and breath methane is controversial. We compared a group of 59 patients with unresected colorectal cancer with a group of control subjects matched for age and sex. We also studied 43 of the cancer patients before and 3-6 months after resection. Sixty-three per cent of the patients with unresected carcinoma and 56% of the control subjects were methane excretors (NS). We found no significant change in methane excretion status after resection. Because recent colonic cleansing has been shown to influence methane production in the colon, 15 breath methane excretors were studied immediately before the start of cleansing, on the day of colonoscopy, and on the 7th day thereafter. Forty per cent became breath-methane-negative on the day of colonoscopy, but all 15 were excretors with a median of 60% of the precleansing concentration on the 7th day. The present study does not confirm an association between breath methane and colorectal cancer. It is unlikely that colonic cleansing procedures influenced the results of this study.
Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1736338&dopt=Abstract constipation laxative colon cleansing
Gastroenterol Nurs. 1991 Dec;14(3):135-7.
Palatability of colonic lavage solution is improved by the addition of artificially sweetened flavored drink mixes.
Gruber M, Fay D, Pudhorodsky T, Lance P.
A frequent complaint of patients asked to drink polyethylene glycol (PEG) colonic lavage solution is the salty flavor. This often results in failure to ingest the entire 4 liters of the solution and compromises bowel cleansing. The purpose of this study was to determine systematically whether the addition of a flavored drink mix sweetened with aspartame to the PEG lavage solution would improve palatability without significantly altering the osmolality of the solution. Eighty-seven (87) staff volunteers participated in a taste test of PEG lavage solutions containing varying amounts of commercially available drink mixes. The solution containing two packages of lemon-flavored KoolAid drink mix sweetened with aspartame was significantly more palatable than the others (p less than 0.005), while osmolality remained within the range specified by the manufacturer of Colyte.
Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1760449&dopt=Abstract constipation laxative colon cleansing
Langenbecks Arch Chir Suppl Kongressbd. 1991;:333-9.
[Mortality and morbidity conference. Perioperative fatalities]
[Article in German]
Pichlmaier H, Wolters U.
Chirurgische Universitatsklinik Koln, Bundesrepublik Deutschland.
Postoperative complications in 4675 patients were investigated. There were specific patterns of complications with significant differences between vascular and general surgery and transplantation. On the basis of test operations (inguinal hernia, cholecystectomy, resection of colon and rectum) it could be shown that differences were ward-specific. Over a period of 12 years, a certain decrease of complication rates could be demonstrated (wound infection, from 9% to 1.25%; pneumonia, from 8% to 2.5%; mortality, from 6.3% to 1.8%). Changes in clinical practice (antibiotic prophylaxis, bowel cleansing, introduction of new techniques, etc.) may be responsible for these improvements. We are convinced that a regular complication conference essentially influences the actions of physicians and nurses.
Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=1793922&dopt=Abstract constipation laxative colon cleansing
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