laxative



References: Laxative







Can J Surg. 2001 Apr;44(2):113-6.
Glutaraldehyde-induced colitis.

Stein BL, Lamoureux E, Miller M, Vasilevsky CA, Julien L, Gordon PH.

Division of Colon and Rectal Surgery, Mortimer B Davis-Jewish General Hospital and McGill University, Montreal, Que.

OBJECTIVE: To describe the etiology and clinical course of acute colitis occurring after flexible endoscopy. DESIGN: Chart review. SETTING: A university teaching hospital. PATIENTS: Eight patients who sought assessment of potential colonic disease. INTERVENTION: Colonoscopy in 5 patients and flexible sigmoidoscopy in 3 patients. The indication for endoscopy was screening in 5 patients, cancer surveillance in 2 patients and preoperative evaluation of colon carcinoma in 1 patient. OUTCOME MEASURES: The relation of presenting symptoms to glutaraldehyde exposure, the response to therapy and the need for further therapy. RESULTS: All patients had abdominal pain, mucus diarrhea and rectal bleeding within 48 hours after endoscopy. Most patients reported that the symptoms started within 12 hours of the procedure. All patients were confirmed by sigmoidoscopy to have colitis within 72 hours of the first endoscopic procedure. One patient required hospitalization. In the first 7 patients several stool cultures were negative for Clostridium difficile using the cytotoxin assay by the cell culture method. Four patients had negative cultures for Yersinia, Salmonella and Shigella spp. Three patients were treated with metronidazole initially. Two patients underwent endoscopic biopsy and examination of the biopsy specimen showed fibrinoleukocytic exudate and ischemic type injury. One patient underwent the scheduled sigmoid resection within 48 hours of endoscopy for a Dukes' stage B adenocarcinoma. Concomitant acute ischemic colitis limited to the mucosa and submucosa was noted in the resected specimen. Symptoms resolved in all patients and follow-up endoscopy revealed normal mucosa. CONCLUSION: The entity of glutaraldehyde-induced colitis should be recogni




Gastrointest Endosc. 2001 Aug;54(2):229-32.
Usefulness of Dennis Colorectal Tube in endoscopic decompression of acute, malignant colonic obstruction.

Horiuchi A, Maeyama H, Ochi Y, Morikawa A, Miyazawa K.

Departments of Gastroenterology and Surgery, Showa Inan General Hospital, Komagane, Japan.

BACKGROUND: Colonoscopic decompression has been attempted in patients with acute colonic obstruction caused by colon cancer to avoid emergency surgery and multiple subsequent operations but has usually been unsuccessful. This is an evaluation of the usefulness of a new device for endoscopic decompression in these patients. METHODS: Nine consecutive patients (6 men, 3 women; 65 to 89 years of age) with acute colonic obstruction resulting from colon cancer underwent endoscopic decompression with a Dennis Colorectal Tube. RESULTS: In all 9 patients (1 with carcinoma of the sigmoid colon, 3 with carcinoma of descending colon, 2 with carcinoma of the transverse colon, 2 with carcinoma of the ascending colon, and 1 with carcinoma of the cecum), endoscopic decompression was successful. After decompressing and cleansing the colon for several days, a one-stage operation was possible in all patients. CONCLUSION: Dennis Colorectal Tube is an excellent device for endoscopic decompression of acute, malignant colonic obstruction.

Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=11474399&dopt=Abstract constipation laxative colon cleansing




AJR Am J Roentgenol. 1979 Nov;133(5):913-5.
Increasing patient complicance in preparing for barium enema examination.

Fordham SD.

Since feces may mimic important lesions of the colon, adequate cleansing is required for a good diagnostic study. An experiment was designed to assess the effect of advance oral and written communication on patient compliance with instruction for preparing the colon for the barium enema. These communication methods were compared against a control group in the extent to which they would encourage patients to more adequately follow cleansing instructions. It was found that each of these increased the quality of the preparation to a similar degree and when combined resulted in the most optimal level of cleansing.

Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=115282&dopt=Abstract constipation laxative colon cleansing



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