laxative



References: Laxative







Minerva Med. 1981 Oct 20;72(40):2689-700.
[Preparation of patients in diagnostic contrast radiography of the urinary and bile tracts and the large intestine]

[Article in Italian]

Albanese A, Carcione A, Notaro P, Salerno G, Traina G.

A preparation schedule including, for clysterisation, a substance based on palmitate, stearate and oleate of sodium of vegetable origin has been experimented in 130 patients of both sexes (70 awaiting contrastography of the urinary and bile ways, and 60 double contrastography of the colon). Excellent results were obtained in urography and colangiocholecystography when the schedule was limited to just one clyster with double dose of Radioced carried out on the same morning as the investigation. For an examination like double contrast clyster, which is more demanding from the viewpoint of correct intestinal cleansing, the number of clysters has to be increased to four. Three, at appropriate intervals, are carried out on the day preceding examination, and the last no more than two hours prior to the clyster. In all four, a double dose of Radioced dissolved in warm water (two litres for each of the first three and a litre and a half for the fourth) is used. Still on double contrast clyster, the preparation schedule requires a three-day diet (the first two involving low-waste foods and the third a liquid diet only) plus 30 g of Epsom salts (and no less than a litre of water) the day before double contrastography.

Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7290472&dopt=Abstract constipation laxative colon cleansing




Gastroenterology. 1980 May;78(5 Pt 1):991-5.
Development of a lavage solution associated with minimal water and electrolyte absorption or secretion.

Davis GR, Santa Ana CA, Morawski SG, Fordtran JS.

Ingestion of large volumes of a balanced electrolyte solution has previously been shown to be an effective method of cleaning the colon for diagnostic studies. However, in this paper we have shown that total gut perfusion with such a solution results in absorption of 2400 ml water and 375 meq of sodium over 3 hr, which is the approximate time required to clean the colon by this technique. This might be hazardous to patients who are unable to readily excrete a salt and water load. We, therefore, designed a solution containing mainly sodium sulfate that was associated with only trivial amounts of water and sodium absorption or secretion during total gut perfusion. This new solution might be useful in colon cleansing before colonoscopy, barium enema, and surgery. In addition, such a solution may have some therapeutic indications, including bowel cleaning in patients with hepatic encephalopathy or as a rapid washout technique for ingested toxins.

Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7380204&dopt=Abstract constipation laxative colon cleansing




Surg Gynecol Obstet. 1981 Jan;152(1):36-8.
Operations on the colon without preoperative oral antibiotic therapy.

Menaker GJ, Litvak S, Bendix R, Michel A, Kerstein MD.

The ideal preparation of the intestine prior to elective colonic resection has been a controversial subject. With the development of new and more effective antibiotics, many modalities of intestinal preparation preoperatively have been used in an effort to reduce the number of infectious complications. Mechanical cleansing of the intestine, when accompanied by perioperative parenteral antibiotics, is adequate preparation prior to resection of the intestine. One hundred consecutive operations upon the colon by one surgeon were the subject of this retrospective study. Approximately 70 per cent of the operations were for carcinoma and the remainder for inflammatory disease. Preparation consisted of the administration of cathartics and saline solution enemas combined with a liquid diet for 48 hours prior to operation. Perioperative parenteral antibiotic therapy was given for 48 to 72 hours or as long as intravenous fluids were administered. All anastomoses were the open, two layer type, using nonabsorbable suture material. All abdominal incisions were closed primarily. There were no operative deaths, anastomotic leaks, intra-abdominal abscesses or fistulas. There were six instances of wound infection. Our results with this type of management compare favorably with those of other surgeons using various modes of preoperative oral antibiotic therapy and suggest that oral preoperative antibiotic therapy may not be necessary in elective operations on the colon.

Laxative online source: www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=7455888&dopt=Abstract constipation laxative colon cleansing



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